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The Denver Broncos visit the Buffalo Bills in what promises to be a high-stakes AFC clash. With both teams fighting for playoff positioning, the Broncos vs Bills best bet revolves around the total points line. Buffalo’s offense ranks top-5 in passing yards, while Denver’s defense has been vulnerable against running quarterbacks—a clear edge for Josh Allen.
Target Allen’s rushing prop (over 35.5 yards) given his tendency to scramble against blitz-heavy defenses. For the Broncos, Courtland Sutton’s receiving line (under 67.5 yards) looks solid—Bills cornerbacks have limited WR1s all season.
The over/under sits at 46.5. Historical data shows divisional-style matchups often go over when both teams have capable offenses. With temperatures dropping in Buffalo, check for wind conditions that could impact kicking.
The broncos vs bills best bet is taking the over 46.5 points combined with Josh Allen anytime touchdown scorer (+175). Buffalo rarely loses at home in December, and Denver’s secondary has allowed multiple passing touchdowns in 6 of 8 games. If the Broncos keep it close, expect a shootout finish. Always compare odds across sportsbooks before locking in—line movement often reveals sharp action.